Ono Pharmaceutical Co., Ltd. (4528.T) stock analysis

In our weekly check, Ono Pharmaceutical Co., Ltd. is graded C (A to F). Of 25 checks on debt, profit, cash flow and trend: 16 pass, warnings: 6, red flags: 3.

About Ono Pharmaceutical Co., Ltd.

Ono Pharmaceutical Co., Ltd. is a Healthcare company (Drug Manufacturers - General) based in Japan, listed on JPX as 4528.T.

What our checks show for 4528.T

Red flags

• The net margin fell by 7.1 points over 5 years, to 15.2%: the company keeps less of each sale as profit.
• Analysts expect revenue to shrink about 2.5% a year.
• The stock has fallen as much as 74% from a peak. Would you have held through that?

Warning signs

• Analysts expect earnings per share to shrink about 2.4% a year.
• Analysts expect the net margin to shrink by 0.3 points from today's 15.2%.
• Revenue grew only 3.2% a year over the last 3 years.
• Earnings per share fell 11.7% a year over the last 3 years.
• Net profit fell 12.9% a year over the last 3 years.
• The stock is still below its previous peak.

Strengths

• Debt is low: 0.13x equity.
• Operating profit covers interest 30.7 times over.
• Operating cash flow is 1.78x net profit: the profit arrives as real cash.
• Free cash flow is 25.9% of revenue: cash for dividends, buybacks or growth.
• The price is 14.2 times earnings (P/E), reasonable for its growth.
• Beta 0.14: the stock usually moves less than the market.

Similar companies

LLY · JNJ · ABBV · MRK · NVS · AZN

Questions

What grade does Ono Pharmaceutical Co., Ltd. (4528.T) have?

In our weekly check, Ono Pharmaceutical Co., Ltd. is graded C (A to F). Of 25 checks on debt, profit, cash flow and trend: 16 pass, warnings: 6, red flags: 3. The grade is a risk check, not a buy or sell recommendation.

What are the main risks of 4528.T stock?

This week's biggest flags for Ono Pharmaceutical Co., Ltd.: Margins falling, Weak revenue forecast, Deep past fall. In total 9 of 25 checks show a warning or a red flag.

What does Ono Pharmaceutical Co., Ltd. do?

Ono Pharmaceutical Co., Ltd. is a Healthcare company (Drug Manufacturers - General) based in Japan, listed on JPX as 4528.T.

The grade is a risk check, not a price forecast, and not investment advice. In our 10-year test (S&P 500, 2016-2026), stocks we graded A or B fell more than 30% 2-3 times less often than D or F, without a lower average return.

Updated 2026-10-31

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