OPKO Health, Inc. (OPK) stock analysis

In our weekly check, OPKO Health, Inc. is graded F (A to F). Of 22 checks on debt, profit, cash flow and trend: 4 pass, warnings: 5, red flags: 13.

About OPKO Health, Inc.

OPKO Health, Inc. is a Healthcare company (Diagnostics & Research) based in the United States, listed on NASDAQ as OPK.

What our checks show for OPK

Red flags

• Operating profit does not cover the interest bill (-3.3x): interest is paid from cash or new debt.
• The net margin fell by 10.7 points over 5 years, to -12.4%: the company keeps less of each sale as profit.
• Operating cash flow is negative while the company reports a profit: the profit does not arrive as cash.
• Weak EPS forecast
• Analysts expect the net margin to shrink by 18 points from today's -12.4%.
• Revenue fell 16.3% a year over the last 3 years.
• Earnings per share fell 40.8% a year over the last 3 years.
• The company is losing money: the net margin is -12.4%.
• Free cash flow is negative (-22.8% of revenue): the business spends more cash than it brings in.
• The price swings a lot: 53.7% annual volatility. Expect large ups and downs.
• The stock has fallen as much as 95% from a peak. Would you have held through that?
• Return on capital (ROCE) is zero or negative: the business does not earn on the money put into it.
• Pay in shares equals 0% of free cash flow: it dilutes shareholders.

Warning signs

• The gross margin fell by 1.8 points, to 31%: costs are rising faster than prices.
• Analysts expect only about 1.2% a year of growth in revenue.
• A small company (market value $1.22 billion): usually riskier and followed by fewer analysts.
• The stock is still below its previous peak.
• Beta 1.5: the stock usually moves more than the market, both up and down.

Strengths

• Actively traded: about 4.2 million shares a day.

Next earnings report: 2026-11-04

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Questions

What grade does OPKO Health, Inc. (OPK) have?

In our weekly check, OPKO Health, Inc. is graded F (A to F). Of 22 checks on debt, profit, cash flow and trend: 4 pass, warnings: 5, red flags: 13. The grade is a risk check, not a buy or sell recommendation.

What are the main risks of OPK stock?

This week's biggest flags for OPKO Health, Inc.: Weak interest cover, Margins falling, Profits not backed by cash. In total 18 of 22 checks show a warning or a red flag.

What does OPKO Health, Inc. do?

OPKO Health, Inc. is a Healthcare company (Diagnostics & Research) based in the United States, listed on NASDAQ as OPK.

When does OPKO Health, Inc. report earnings next?

The next earnings report is expected on 2026-11-04. We re-run the checks every week, so the grade can change after it.

The grade is a risk check, not a price forecast, and not investment advice. In our 10-year test (S&P 500, 2016-2026), stocks we graded A or B fell more than 30% 2-3 times less often than D or F, without a lower average return.

Updated 2026-10-24

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